The South Central Branch of ASM, founded on July 7, 1947 and approved by the American Society of Microbiology (formally Society of American Bacteriologists) as the 24th approved branch, includes Arkansas, Louisiana and Mississippi.

Since commencement of the first meeting in 1977, the South Central Branch of the American Society for Microbiology has held meetings annually, rotating throughout the three states comprising the branch. These annual meetings provide microbiologists the chance to exchange information and gain insight across a variety of scientific disciplines.